Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312501 | 0.79 | HTR1D (0.44) | HTR1DHTR1BHTR3EHTR3BHTR3A | |
| SCHEMBL9313535 | 0.68 | RECQL (0.33) | HTR1DHTR1B | |
| SCHEMBL9313082 | 0.67 | MEN1 (0.37) | HTR1DHTR1BHTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL8130718 | 0.67 | HTR1D (0.38) | HTR1DHTR1B | |
| SCHEMBL9312616 | 0.64 | HTR3E (0.44) | HTR1DHTR1BHTR3EHTR3BHTR3A | |
| SCHEMBL1021475 | 0.62 | AKR1B1 (0.54) | HTR1DHTR1BHTR3EHTR3BHTR3A | |
| SCHEMBL16275249 | 0.61 | NOS1 (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL10424357 | 0.54 | — | — | |
| SCHEMBL160546 | 0.54 | — | — | |
| SCHEMBL3074219 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5366996-A | Administering hydroxamic acids | ELFORD HOWARD L (US) | 1994-11-22 | — | — | US | disclosed |
| US-5183828-A | Ribonucleotide reductase inhibitor and free radical scavenger | RIET BARTHOLOMEUS VAN T (US) | 1993-02-02 | — | — | US | disclosed |
| US-4942253-A | INHIBITORS OF RIBONUCLEOTIDE REDUCTASE, ANTITUMOR AGENTS, LEUKEMIA, FREE RADICAL SCAVENGERS | RIET BARTHOLOMEUS VAN T (US) | 1990-07-17 | — | — | US | disclosed |
| US-4623659-A | RIBONUCLEOTIDE REDUCTASE INHIBITORS | RIET BARTHOLOMEUS VAN T (US) | 1986-11-18 | — | — | US | disclosed |