Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 16/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 12/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830471 | 0.78 | CYP1A2 (0.51) | PTGS1PTGS2CA1CA2ALOX5 | |
| SCHEMBL9180604 | 0.76 | PTGS1 (0.68) | PTGS1PTGS2CA1CA2ALOX5 | |
| SCHEMBL9457150 | 0.76 | SMPD3 (0.58) | PTGS1PTGS2CA1CA2ALOX5 | |
| SCHEMBL10785875 | 0.76 | TNF (0.60) | PTGS1PTGS2 | |
| SCHEMBL9179869 | 0.75 | PTGS1 (1.00) | PTGS1PTGS2CA1CA2ALOX5 | |
| SCHEMBL9181713 | 0.75 | CA1 (0.53) | PTGS1PTGS2CA1CA2ALOX5 | |
| SCHEMBL9185074 | 0.75 | PTGS1 (0.66) | PTGS1PTGS2CA1CA2ALOX5 | |
| SCHEMBL25380571 | 0.75 | PTGS1 (0.40) | PTGS1PTGS2ALOX5 | |
| SCHEMBL8868246 | 0.75 | KDM4E (0.60) | PTGS1PTGS2CA1CA2ALOX5 | |
| SCHEMBL803157 | 0.75 | CA2 (1.00) | PTGS1PTGS2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5350857-A | Metallized thiazole dyes for images | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-09-27 | — | — | US | disclosed |
| US-5284812-A | Coordination compounds formed thereof with transition metals; pressure sensitive carbonless copy paper | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-02-08 | — | — | US | disclosed |