Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | TTPA | P49638 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312775 | 0.88 | ALOX5 (0.44) | KMT2AMEN1TTPAALOX5SMN1; SMN2 | |
| SCHEMBL9010322 | 0.84 | TTPA (0.54) | KMT2AMEN1PDE4APDE3ATTPA | |
| SCHEMBL9257714 | 0.83 | TTPA (0.48) | KMT2AMEN1PDE4APDE3ATTPA | |
| SCHEMBL9312856 | 0.82 | MEN1 (0.51) | KMT2AMEN1PDE4APDE3ATTPA | |
| SCHEMBL9075119 | 0.80 | MEN1 (0.59) | KMT2AMEN1PDE4APDE3ATTPA | |
| SCHEMBL9655667 | 0.79 | KMT2A (0.48) | KMT2AMEN1PDE4APDE3ATTPA | |
| SCHEMBL11706578 | 0.78 | MEN1 (0.61) | KMT2AMEN1PDE4APDE3ATTPA | |
| SCHEMBL11706067 | 0.78 | MEN1 (0.61) | KMT2AMEN1PDE4APDE3ATTPA | |
| SCHEMBL11705132 | 0.78 | MEN1 (0.61) | KMT2AMEN1PDE4APDE3ATTPA | |
| SCHEMBL11703482 | 0.77 | MEN1 (0.60) | KMT2AMEN1PDE4APDE3ATTPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |