Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | TTPA | P49638 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313511 | 0.88 | MEN1 (0.49) | ALOX5MEN1TTPAKMT2APPARG | |
| SCHEMBL9312755 | 0.85 | PTGS1 (0.55) | ALOX5NR1I2PTGS1PTGS2CYP1A2 | |
| SCHEMBL9313793 | 0.83 | ALOX5 (0.47) | ALOX5NR1I2MAPTLMNAPTGS1 | |
| SCHEMBL9312699 | 0.81 | MAPT (0.49) | ALOX5NR1I2MAPTLMNAPTGS1 | |
| SCHEMBL9255192 | 0.80 | PTGS1 (0.48) | ALOX5NR1I2MAPTLMNAPTGS1 | |
| SCHEMBL9096916 | 0.75 | CYP3A4 (0.56) | ALOX5NR1I2MAPTLMNAPTGS1 | |
| SCHEMBL9094963 | 0.75 | CYP3A4 (0.56) | ALOX5NR1I2MAPTLMNAPTGS1 | |
| SCHEMBL9314064 | 0.75 | ALOX5 (0.44) | ALOX5NR1I2MAPTLMNAPTGS1 | |
| SCHEMBL11707684 | 0.75 | ALOX5 (0.51) | ALOX5NR1I2MAPTLMNAPTGS1 | |
| SCHEMBL11706911 | 0.75 | ALOX5 (0.51) | ALOX5NR1I2MAPTLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |