Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | TTPA | P49638 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312762 | 0.90 | ALOX5 (0.46) | ALOX5MAPTLMNAPTGS1PTGS2 | |
| SCHEMBL9312848 | 0.84 | MEN1 (0.48) | ALOX5MEN1TTPAKMT2A | |
| SCHEMBL9313918 | 0.83 | MAPT (0.45) | ALOX5MAPTLMNAPTGS1PTGS2 | |
| SCHEMBL9313793 | 0.82 | ALOX5 (0.47) | ALOX5MAPTLMNAPTGS1PTGS2 | |
| SCHEMBL9314088 | 0.78 | PTGS1 (0.55) | ALOX5PTGS1PTGS2TTPACYP1A2 | |
| SCHEMBL9314926 | 0.77 | ALOX5 (0.42) | ALOX5MAPTLMNAPTGS1PTGS2 | |
| SCHEMBL9312699 | 0.76 | MAPT (0.49) | ALOX5MAPTLMNAPTGS1PTGS2 | |
| SCHEMBL7531573 | 0.76 | MAPT (0.54) | ALOX5MAPTLMNAPTGS1PTGS2 | |
| SCHEMBL9312868 | 0.75 | ALOX5 (0.46) | ALOX5MAPTLMNAPTGS1PTGS2 | |
| SCHEMBL7535095 | 0.74 | ALOX5 (0.61) | ALOX5MAPTLMNAPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |