Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 13/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311736 | 0.86 | MAPK10 (0.61) | MAPK10ALDH1A1LMNAMAPK14MAPK9 | |
| Hydrochloric Acid SCHEMBL9312979 | 0.85 | MAPK10 (0.60) | MAPK10ALDH1A1LMNAMAPK14MAPK9 | |
| SCHEMBL9311746 | 0.81 | ALDH1A1 (0.68) | MAPK10ALDH1A1LMNAMAPK14MAPK9 | |
| Hydrochloric Acid SCHEMBL27320100 | 0.78 | PKM (0.55) | MAPK10ALDH1A1LMNAMAPK14MAPK9 | |
| SCHEMBL9311574 | 0.77 | MAPK10 (0.61) | MAPK10ALDH1A1LMNAMAPK14MAPK9 | |
| SCHEMBL4439370 | 0.77 | MAPK10 (0.58) | MAPK10ALDH1A1LMNAMAPK14MAPK9 | |
| Hydrochloric Acid SCHEMBL9313359 | 0.76 | MAPK10 (0.60) | MAPK10ALDH1A1LMNAMAPK14MAPK9 | |
| SCHEMBL28931630 | 0.76 | ALDH1A1 (0.79) | MAPK10ALDH1A1LMNAMAPK14MAPK9 | |
| SCHEMBL30597523 | 0.76 | ALDH1A1 (0.79) | MAPK10ALDH1A1LMNAMAPK14MAPK9 | |
| SCHEMBL9312347 | 0.72 | MAPK10 (0.63) | MAPK10ALDH1A1LMNAMAPK14MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE34630-E | Antagonist for platelet activating factor | EUROCELTIQUE, S.A. (LU) | 1994-06-07 | — | — | US | disclosed |
| EP-0422328-A2 | Substituted isoquinolines and their use | Euro-Celtique S.A. (LU) | 1991-04-17 | — | — | EP | disclosed |
| US-4956371-A | PLATELET ACTIVATING FACTOR | EUROCELTIQUE, S.A. (LU) | 1990-09-11 | — | — | US | disclosed |