Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312477 | 0.83 | EGFR (0.44) | TYRMAPTTP53CYP3A4ALOX15 | |
| SCHEMBL28875498 | 0.79 | MEN1 (0.58) | TYRMEN1KMT2AALOX5 | |
| SCHEMBL9313064 | 0.76 | TYR (0.52) | TYRMEN1KMT2AALOX5MAPT | |
| SCHEMBL9313910 | 0.76 | MEN1 (0.48) | MEN1KMT2AMAPTCYP3A4ALOX15 | |
| SCHEMBL9313957 | 0.75 | MEN1 (0.34) | TYRMEN1KMT2AMAPTTDP1 | |
| SCHEMBL29419312 | 0.74 | TYR (0.60) | TYRMEN1KMT2AALOX5TSHR | |
| SCHEMBL9313934 | 0.74 | ESR2 (0.37) | MEN1KMT2AMAPTCYP3A4TDP1 | |
| SCHEMBL3022818 | 0.74 | TYR (0.60) | TYRMEN1KMT2AALOX5MAPT | |
| SCHEMBL156238 | 0.74 | TYR (0.60) | TYRMEN1KMT2AALOX5TSHR | |
| SCHEMBL28718751 | 0.74 | TYR (0.60) | TYRMEN1KMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5366996-A | Administering hydroxamic acids | ELFORD HOWARD L (US) | 1994-11-22 | — | — | US | disclosed |
| US-5183828-A | Ribonucleotide reductase inhibitor and free radical scavenger | RIET BARTHOLOMEUS VAN T (US) | 1993-02-02 | — | — | US | disclosed |
| US-4942253-A | INHIBITORS OF RIBONUCLEOTIDE REDUCTASE, ANTITUMOR AGENTS, LEUKEMIA, FREE RADICAL SCAVENGERS | RIET BARTHOLOMEUS VAN T (US) | 1990-07-17 | — | — | US | disclosed |
| US-4623659-A | RIBONUCLEOTIDE REDUCTASE INHIBITORS | RIET BARTHOLOMEUS VAN T (US) | 1986-11-18 | — | — | US | disclosed |