Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9718521 | 1.00 | CYP11B1 (0.35) | CYP11B1CYP11B2DHODHACACBGPR139 | |
| SCHEMBL9313402 | 1.00 | CYP11B1 (0.35) | CYP11B1CYP11B2DHODHACACBGPR139 | |
| SCHEMBL8381945 | 0.91 | CHRNB1 (0.34) | CYP11B1CYP11B2DHODHACACBKCNH2 | |
| SCHEMBL8381946 | 0.91 | CHRNB1 (0.34) | CYP11B1CYP11B2DHODHACACBKCNH2 | |
| SCHEMBL9313058 | 0.91 | CHRNB1 (0.34) | CYP11B1CYP11B2DHODHACACBKCNH2 | |
| SCHEMBL8383724 | 0.91 | CYP11B1 (0.36) | CYP11B1CYP11B2DHODHACACBGPR139 | |
| SCHEMBL9313556 | 0.91 | CYP11B1 (0.36) | CYP11B1CYP11B2DHODHACACBGPR139 | |
| SCHEMBL9718529 | 0.90 | MAPK10 (0.33) | CYP11B1CYP11B2RXRAGRIN1GRIN2B | |
| SCHEMBL9312596 | 0.90 | MAPK10 (0.33) | CYP11B1CYP11B2RXRAGRIN1GRIN2B | |
| SCHEMBL9312602 | 0.90 | MAPK10 (0.33) | CYP11B1CYP11B2RXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292452-A | Electrooptical devices; high dielectric anisotropy, low rotation viscosity, short response time | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |