Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 3/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | LYN | P07948 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312602 | 1.00 | MAPK10 (0.33) | MAPK10S1PR3S1PR1SLC6A3NPC1 | |
| SCHEMBL9312596 | 1.00 | MAPK10 (0.33) | MAPK10S1PR3S1PR1SLC6A3NPC1 | |
| SCHEMBL8381988 | 0.91 | S1PR3 (0.34) | MAPK10S1PR3S1PR1SLC6A3NPC1 | |
| SCHEMBL9312443 | 0.91 | S1PR3 (0.34) | MAPK10S1PR3S1PR1SLC6A3NPC1 | |
| SCHEMBL8381946 | 0.90 | CHRNB1 (0.34) | S1PR3S1PR1NPC1RAB9ACYP11B1 | |
| SCHEMBL9718521 | 0.90 | CYP11B1 (0.35) | CYP11B1CYP11B2RXRAGRIN1GRIN2B | |
| SCHEMBL8381945 | 0.90 | CHRNB1 (0.34) | S1PR3S1PR1NPC1RAB9ACYP11B1 | |
| SCHEMBL9313403 | 0.90 | CYP11B1 (0.35) | CYP11B1CYP11B2RXRAGRIN1GRIN2B | |
| SCHEMBL9313058 | 0.90 | CHRNB1 (0.34) | S1PR3S1PR1NPC1RAB9ACYP11B1 | |
| SCHEMBL9313402 | 0.90 | CYP11B1 (0.35) | CYP11B1CYP11B2RXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475273-A1 | Halogenated alcenyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |