Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | GABRP | O00591 | 1/20 | 0.54 |
| ▸ | GABRD | O14764 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29756559 | 0.83 | DYRK1A (0.60) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL10169901 | 0.83 | DYRK1A (0.60) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL28667621 | 0.80 | MAPT (0.56) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL10708983 | 0.80 | MAPT (0.59) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL31327490 | 0.80 | KIF11 (0.44) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL28073835 | 0.80 | PDPK1 (0.46) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL29472418 | 0.80 | MAPT (0.52) | MAPTKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL23500446 | 0.79 | MEN1 (0.52) | MEN1KMT2ATDO2POLBHDAC1 | |
| SCHEMBL31327501 | 0.79 | MEN1 (0.52) | MEN1KMT2ATDO2POLBHDAC1 | |
| SCHEMBL29817742 | 0.78 | MAPT (0.53) | MAPTKDM4ELMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104628723-B | A kind of banisterine benzoyl urea compound and its preparation method and application | SOUTH CHINA AGRICULTURAL UNIVERSITY (CN) | 2016-06-01 | — | — | CN | claimed |
| CN-118994153-A | Beta-carboline naphthoquinone derivative and preparation method and medical application thereof | 南通大学 | 2024-11-22 | — | — | CN | disclosed |
| CN-104628723-B | A kind of banisterine benzoyl urea compound and its preparation method and application | SOUTH CHINA AGRICULTURAL UNIVERSITY (CN) | 2016-06-01 | — | — | CN | disclosed |
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | disclosed |