Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27979876 | 0.82 | KIF11 (0.44) | KIF11ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL9313465 | 0.80 | MAPT (0.56) | KIF11CA5AALDH1A1HSD17B10HPGD | |
| SCHEMBL28433689 | 0.79 | MAPT (0.50) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| SCHEMBL27979743 | 0.78 | MAPT (0.46) | KIF11ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL27899818 | 0.77 | KMT2A (0.52) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| SCHEMBL29756407 | 0.74 | TDO2 (0.65) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| SCHEMBL2733976 | 0.74 | TDO2 (0.65) | ALDH1A1HSD17B10HPGDKDM4EMAPT | |
| SCHEMBL23876077 | 0.74 | MAPT (0.71) | KIF11ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL4543061 | 0.74 | MEN1 (0.60) | CA5AALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL23500446 | 0.72 | MEN1 (0.52) | KIF11MEN1KMT2ATDO2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994153-A | Beta-carboline naphthoquinone derivative and preparation method and medical application thereof | 南通大学 | 2024-11-22 | — | — | CN | disclosed |