Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313695 | 0.89 | ACP3 (0.40) | ACP3MMP8KIF11MRGPRX4KDM4E | |
| SCHEMBL7387975 | 0.77 | CYP1A2 (0.41) | KIF11L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9312893 | 0.74 | PTPN1 (0.39) | KIF11MRGPRX4KDM4EALDH1A1NPC1 | |
| SCHEMBL5010732 | 0.67 | ACP3 (0.42) | ACP3MMP8KIF11KDM4EHPGD | |
| SCHEMBL9313693 | 0.67 | TDP1 (0.41) | ACP3MMP8HPGDTDP1KMT2A | |
| SCHEMBL8377365 | 0.65 | ALDH1A1 (0.44) | ACP3KDM4EHPGDTDP1ALDH1A1 | |
| SCHEMBL8376830 | 0.65 | ACP3 (0.45) | ACP3KIF11KDM4EHPGDTDP1 | |
| SCHEMBL6039609 | 0.65 | ACP3 (0.43) | ACP3MMP8KIF11HPGDALDH1A1 | |
| SCHEMBL7387979 | 0.65 | CYP1A2 (0.43) | KIF11SMN1; SMN2 | |
| SCHEMBL29440057 | 0.65 | ACP3 (0.43) | ACP3MMP8KIF11HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330978-A | Cardiovascular disorders, hypotensive agents, vasodilation | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-07-19 | — | — | US | disclosed |