Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22051459 | 0.80 | GRIN2D (0.47) | LMNAALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL22053012 | 0.79 | GRIN2D (0.55) | LMNAALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8279944 | 0.79 | LMNA (0.63) | LMNAALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL16443399 | 0.78 | GRIN2D (0.57) | LMNAALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5550228 | 0.78 | GRIN2D (0.57) | LMNAALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1794953 | 0.76 | GRIN2D (0.74) | LMNAALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1794951 | 0.76 | GRIN2D (0.74) | LMNAALDH1A1GRIN2DGRIN3BGRIN1 | |
| Phosphine SCHEMBL28553521 | 0.76 | GRIN2D (0.55) | LMNAALDH1A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL17229422 | 0.75 | ALDH1A1 (0.59) | LMNAALDH1A1MGLLTSHRMEN1 | |
| SCHEMBL6433208 | 0.75 | ALDH1A1 (0.64) | LMNAALDH1A1TSHRMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286752-A | Antiarrhythmic diarylamidines | STERLING WINTHROP INC. (US) | 1994-02-15 | — | — | US | disclosed |