Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370568 | 1.00 | EPHX1 (0.49) | EPHX1ALOX5CTSKRENCTSD | |
| SCHEMBL17276029 | 0.98 | EPHX1 (0.46) | EPHX1ALOX5CTSKRENCTSD | |
| SCHEMBL28234483 | 0.94 | EPHX1 (0.42) | EPHX1ALOX5CTSKRENCTSD | |
| SCHEMBL17069436 | 0.89 | — | — | |
| SCHEMBL12540125 | 0.89 | — | — | |
| SCHEMBL13235676 | 0.81 | CTSK (0.42) | CTSKRENCTSLCTSB | |
| SCHEMBL7794348 | 0.81 | LTA4H (0.46) | CTSKCTSLCTSB | |
| SCHEMBL13879136 | 0.81 | CTSK (0.42) | CTSKRENCTSLCTSB | |
| SCHEMBL14947101 | 0.81 | LTA4H (0.46) | CTSKCTSLCTSB | |
| SCHEMBL19817250 | 0.81 | LTA4H (0.46) | CTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1512983-A | Compounds and compositions as cathepsins inhibitors | AXYSҩ�﹫˾ | 2004-07-14 | — | — | CN | claimed |
| US-10954236-B2 | Tyrosine amide derivatives as Rho-Kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2021-03-23 | — | — | US | disclosed |
| WO-2020059715-A1 | FILM FOR MANUFACTURING MOLD, MOLDING METHOD, MOLDED ARTICLE, AND CURABLE COMPOSITION FOR MANUFACTURING MOLD | 富士フイルム株式会社 | 2020-03-26 | — | — | WO | disclosed |
| US-20200079774-A1 | TYROSINE AMIDE DERIVATIVES AS RHO- KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2020-03-12 | — | — | US | disclosed |
| WO-2020031079-A1 | ORGANIC INORGANIC COMPOSITE PARTICLE, METHOD FOR PRODUCING SAME, AND APPLICATION THEREOF | 積水化成品工業株式会社 | 2020-02-13 | — | — | WO | disclosed |
| CN-110475792-A | Enumerate BTA system (co) polymer and containing its ultraviolet-absorbing coating and be coated with the film of the coating | SHIN NAKAMURA CHEMICAL CO LTD | 2019-11-19 | — | — | CN | disclosed |
| CN-110322790-A | Flexible display apparatus covers substrate and the flexible display apparatus using it | 律胜科技股份有限公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-110062774-A | Preparation method of acrylonitrile polymer for producing carbon fiber | 株式会社LG化学 | 2019-07-26 | — | — | CN | disclosed |
| CN-110007558-A | Composition, insulating materials and its preparation method comprising it | 财团法人工业技术研究院 | 2019-07-12 | — | — | CN | disclosed |
| CN-107614568-B | Fluoropolymer resin with formula 1 or formula 2, the then film containing it and the display device that is connected by then film | 三星SDI株式会社 | 2019-06-11 | — | — | CN | disclosed |
| US-9296698-B2 | Amino heteroaryl compounds as beta-secretase modulators and methods of use | AMGEN INC. (US) | 2016-03-29 | — | — | US | disclosed |
| US-20120329830-A1 | Amino Heteroaryl Compounds as Beta-Secretase Modulators and Methods of Use | AMGEN INC. (US) | 2012-12-27 | — | — | US | disclosed |
| EP-2504315-A1 | AMINO HETEROARYL COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE | Amgen Inc. (US) | 2012-10-03 | — | — | EP | disclosed |
| WO-2011063233-A1 | AMINO HETEROARYL COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE | AMGEN INC. (US) | 2011-05-26 | — | — | WO | disclosed |
| CN-101715458-A | Polymeric dispersions and application thereof | PEACH STATE LABS INC | 2010-05-26 | — | — | CN | disclosed |
| CN-100386376-C | Anisotropic conductive film forming composition | CHEIL IND INC (KR) | 2008-05-07 | — | — | CN | disclosed |
| CN-1796453-A | Anisotropic conductive film forming composition | CHEIL IND INC (KR) | 2006-07-05 | — | — | CN | disclosed |
| CN-1512983-A | Compounds and compositions as cathepsins inhibitors | AXYSҩ�﹫˾ | 2004-07-14 | — | — | CN | disclosed |
| CN-1364155-A | N-Cyanomethyl amides as protease inhibitors | AXYS PHARM INC (US) | 2002-08-14 | — | — | CN | disclosed |
| US-4235782-A | Perfluoro(4-methyl-2-oxabicyclo[4.4.0]decane) and method for manufacture thereof | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY, MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) | 1980-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10954236-B2 | Tyrosine amide derivatives as Rho-Kinase inhibitors | ROCK1, ROCK2, CIT | EPHX1 810/4885ALOX5 1975/4885CTSK 1578/4885 |
| US-20120329830-A1 | Amino Heteroaryl Compounds as Beta-Secretase Modulators and Methods of Use | BACE1, BACE2, APP | EPHX1 310/4885ALOX5 1746/4885CTSK 852/4885 |
| US-20200079774-A1 | TYROSINE AMIDE DERIVATIVES AS RHO- KINASE INHIBITORS | ROCK1, ROCK2, CIT | EPHX1 810/4885ALOX5 1975/4885CTSK 1578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.