Morpholine

Morpholine

SCHEMBL9314682

C1COCCN1.CCCNC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.37
KDM4E B2RXH2 3/20 0.37
LMNA P02545 1/20 0.37
ALDH1A1 P00352 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
GNAI3 P08754 2/20 0.35
GNAO1 P09471 2/20 0.35
GNAI1 P63096 2/20 0.35
KMT2A Q03164 2/20 0.33
SLC2A1 P11166 1/20 0.33
MEN1 O00255 1/20 0.33
CYP2C9 P11712 1/20 0.33
RECQL P46063 1/20 0.33
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4533799 0.85 GAA (0.46) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL8434608 0.75 GAA (0.50) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL39399 0.74 SLC2A1 (0.44) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL5250714 0.73 GNAI3 (0.49) GAAKDM4ELMNAALDH1A1NPSR1
Ammonia Solution, Strong SCHEMBL16679627 0.73 SLC2A1 (0.43) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL11235208 0.72 SLC2A1 (0.40) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL18935690 0.72 ALDH1A1 (0.40) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL8762446 0.72 GAA (0.47) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL8432690 0.72 SLC2A1 (0.50) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL11212575 0.71 GNAI3 (0.51) GAAKDM4ELMNAALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5336706-A Radiation, heat and oxidation resistance for Polypropylene fibers CIBA-GEIGY CORPORATION (US) 1994-08-09 US disclosed
US-5256787-A Chemical intermediates for piperidine triazine; photostability , radiation, oxidation and heat resistance CIBA-GEIGY CORPORATION (US) 1993-10-26 US disclosed
US-5187275-A Light, heat and oxidation stabilizers CIBA-GEIGY CORPORATION (US) 1993-02-16 US disclosed
EP-0479724-A2 Piperidine-triazine compounds for use as stabilisers for organic materials CIBA-GEIGY AG (CH) 1992-04-08 EP disclosed