SCHEMBL9314727

SCHEMBL9314727

C=CCOC(=O)NCC(CNC(=O)OCC=C)C(=O)C[C@H]1NC(=O)[C@@H]1[C@@H](C)O

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 6/20 0.33
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9314746 0.88
SCHEMBL9670030 0.86 CASP1 (0.30) CASP1
SCHEMBL9313354 0.85
SCHEMBL9428268 0.78 TDP1 (0.35)
SCHEMBL9315470 0.76
SCHEMBL9313385 0.76 FAAH (0.32) CASP1FAAH
SCHEMBL9313356 0.76
SCHEMBL9315523 0.75 FAAH (0.30) FAAH
SCHEMBL9387545 0.74 CASP1 (0.36) CASP1
SCHEMBL9596420 0.73 CASP1 (0.33) CASP1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5286721-A Antimicrobial agents FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1994-02-15 US disclosed
EP-0506982-A1 1-AZABICYCLO 3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-10-07 EP disclosed
WO-1992006978-A1 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-04-30 WO disclosed