Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 12/20 | 0.50 |
| ▸ | RORA | P35398 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840490 | 0.85 | PTGDR2 (0.47) | KMT2A | |
| SCHEMBL9811752 | 0.84 | MRGPRX4 (0.48) | NR5A1RORAKDM4ENPC1NPSR1 | |
| SCHEMBL403443 | 0.82 | IDH1 (0.55) | NPSR1ALDH1A1IDH1LMNAL3MBTL1 | |
| SCHEMBL11210510 | 0.82 | IDH1 (0.51) | KDM4ENPC1ALDH1A1IDH1LMNA | |
| SCHEMBL3990976 | 0.81 | IDH1 (0.58) | NPSR1MAPTIDH1LMNAL3MBTL1 | |
| SCHEMBL9571180 | 0.80 | HPGD (0.44) | NR5A1RORAKDM4ENPC1NPSR1 | |
| SCHEMBL9571181 | 0.79 | HPGD (0.59) | ALDH1A1LMNAL3MBTL1HPGDKMT2A | |
| SCHEMBL10646208 | 0.79 | IDH1 (0.50) | KDM4EALDH1A1IDH1LMNAL3MBTL1 | |
| SCHEMBL11083861 | 0.78 | IDH1 (0.52) | ALDH1A1MAPTIDH1LMNAL3MBTL1 | |
| SCHEMBL11154363 | 0.77 | LMNA (0.53) | NR5A1KDM4EALDH1A1MAPTIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300676-A | Herbicidal fluorine-substituted alpha-(5-aryloxynaphthalen-1-yl-oxy)-propionic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| EP-0534239-A2 | Derivatives of alpha-(5-dichlorphenoxy-naphthalen-1-yl-oxy)propionic acid as herbicides | BAYER AG (DE) | 1993-03-31 | — | — | EP | disclosed |
| WO-1992018467-A1 | CYANOPHENOXYNAPHTHYL OXYCARBOXYLIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-10-29 | — | — | WO | disclosed |
| EP-0508263-A2 | Derivatives of alpha-(5 aryloxy-1 naphthyloxy)-carboxylic acid | BAYER AG (DE) | 1992-10-14 | — | — | EP | disclosed |
| EP-0453842-A2 | Fluor subsituted derivatives of alpha-(5-aryloxy-naphthalen-1-yloxy)propionic acid | BAYER AG (DE) | 1991-10-30 | — | — | EP | disclosed |