Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 6/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RORA | P35398 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644424 | 0.89 | MRGPRX4 (0.45) | MRGPRX4FFAR1 | |
| SCHEMBL9646555 | 0.87 | PTGDR2 (0.50) | MRGPRX4FFAR1PTGDR2TSHR | |
| SCHEMBL4007944 | 0.87 | MRGPRX4 (0.51) | MRGPRX4FFAR1PTGDR2 | |
| SCHEMBL9563083 | 0.86 | SMN1; SMN2 (0.50) | NR5A1KDM4ERORANPC1ALDH1A1 | |
| SCHEMBL11119306 | 0.85 | FFAR1 (0.51) | MRGPRX4FFAR1KDM4ENPSR1MAPT | |
| SCHEMBL9571181 | 0.85 | HPGD (0.59) | MRGPRX4FFAR1ALDH1A1 | |
| SCHEMBL9314751 | 0.84 | NR5A1 (0.50) | NR5A1KDM4ERORANPC1ALDH1A1 | |
| SCHEMBL10963334 | 0.83 | FFAR1 (0.58) | MRGPRX4FFAR1PTGDR2MAPT | |
| SCHEMBL9633459 | 0.81 | FFAR1 (0.52) | MRGPRX4FFAR1PTGDR2 | |
| SCHEMBL10644204 | 0.81 | FFAR1 (0.52) | MRGPRX4FFAR1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1113331-A | — | — | None | — | — | JP | disclosed |
| EP-0309864-B1 | ALPHA-(5-ARYLOXY-NAPHTHALEN-1-YL-OXY)-PROPIONIC-ACID DERIVATIVES | BAYER AG (DE) | 1991-05-22 | — | — | EP | disclosed |
| JP-H01113331-A | ALPHA-(5-ARYLOXYNAPHTHALEN-1-YLOXY)-PROPIONIC ACID DERIVATIVE | BAYER AG | 1989-05-02 | — | — | JP | disclosed |