Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11172110 | 0.85 | CTBP2 (0.62) | KCNQ2CTBP2TAAR1HTR3EHTR3B | |
| SCHEMBL9316487 | 0.84 | ALOX5 (0.47) | KCNQ2ALOX5KMT2AMAPTALDH1A1 | |
| SCHEMBL9771702 | 0.84 | RAF1 (0.52) | KCNQ2CNR1CTBP2TAAR1HTR3E | |
| Hydrochloric Acid SCHEMBL9314791 | 0.82 | RAF1 (0.51) | KCNQ2CNR1CTBP2TAAR1HTR3E | |
| SCHEMBL5954217 | 0.81 | TAAR1 (0.53) | KCNQ2CTBP2TAAR1HTR3EHTR3B | |
| SCHEMBL9315539 | 0.79 | MAPT (0.52) | KCNQ2CTBP2TAAR1HTR3EHTR3B | |
| SCHEMBL2553049 | 0.78 | KMT2A (0.54) | CNR1HDAC1HDAC6KMT2AL3MBTL1 | |
| SCHEMBL7144102 | 0.78 | CTBP2 (0.56) | KCNQ2CTBP2HTR3EHTR3BHTR3A | |
| SCHEMBL3825118 | 0.78 | HDAC1 (0.51) | CNR1HDAC1HDAC6KMT2AL3MBTL1 | |
| SCHEMBL11178925 | 0.78 | CTBP2 (0.56) | CNR1CTBP2HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006563-A | Alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-04-09 | — | — | US | claimed |
| US-5300527-A | Administering anticholinergic agents for treating the memory dysfunction | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-04-05 | — | — | US | disclosed |
| US-5177111-A | Analgesic | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0432719-A1 | Alkylamino- and alkylaminoalkyl diarylketones, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-06-19 | — | — | EP | disclosed |
| US-5006563-A | Alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-04-09 | — | — | US | disclosed |