Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9314770 | 0.84 | KCNQ2 (0.52) | ALOX5KCNQ2ALDH1A1MAPTKMT2A | |
| SCHEMBL9315545 | 0.80 | KDM4E (0.47) | MAOAMAOBKDM4ENR4A2TDP1 | |
| SCHEMBL9315508 | 0.77 | KDM4E (0.50) | MAOAMAOBKDM4ENR4A2TDP1 | |
| SCHEMBL29955055 | 0.75 | LMNA (0.63) | KDM4EALDH1A1MAPK1HTTMCL1 | |
| SCHEMBL9911815 | 0.75 | APP (0.51) | KDM4EALDH1A1MAPTHTTAPP | |
| SCHEMBL7996336 | 0.75 | LMNA (0.63) | KDM4EALDH1A1MAPK1HTTMCL1 | |
| SCHEMBL9771702 | 0.75 | RAF1 (0.52) | ALOX5MAOAMAOBKDM4EKCNQ2 | |
| SCHEMBL1427808 | 0.74 | SMN1; SMN2 (0.58) | KDM4EALDH1A1MAPTHTTAPP | |
| SCHEMBL1813963 | 0.74 | APP (0.50) | KDM4EALDH1A1MAPTMAPK1HTT | |
| Hydrochloric Acid SCHEMBL9314791 | 0.74 | RAF1 (0.51) | ALOX5MAOAMAOBKDM4EKCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006563-A | Alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-04-09 | — | — | US | claimed |
| US-5300527-A | Administering anticholinergic agents for treating the memory dysfunction | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-04-05 | — | — | US | disclosed |
| US-5177111-A | Analgesic | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0432719-A1 | Alkylamino- and alkylaminoalkyl diarylketones, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-06-19 | — | — | EP | disclosed |
| US-5006563-A | Alzheimer's disease | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-04-09 | — | — | US | disclosed |