Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MLYCD | O95822 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315502 | 1.00 | POLB (0.39) | POLBKDM4EMAPTKMT2ALMNA | |
| SCHEMBL9315410 | 0.82 | POLB (0.50) | POLBKDM4EMAPTKMT2ANPSR1 | |
| SCHEMBL9314753 | 0.81 | PTGS2 (0.46) | MAPTKMT2ALMNATSHR | |
| SCHEMBL9315517 | 0.81 | PTGS2 (0.46) | MAPTKMT2ALMNATSHR | |
| SCHEMBL13410336 | 0.78 | CA1 (0.51) | POLBKDM4EMAPTKMT2ALMNA | |
| SCHEMBL12267961 | 0.77 | NR1H4 (0.47) | MAPTLMNASMN1; SMN2 | |
| SCHEMBL24208336 | 0.74 | POLB (0.38) | POLBKMT2ALMNATSHRMLYCD | |
| SCHEMBL11857185 | 0.74 | MAPT (0.47) | KDM4EMAPTKMT2ALMNAHTT | |
| SCHEMBL29120823 | 0.74 | PTPN5 (0.46) | — | |
| SCHEMBL3279844 | 0.73 | KMT2A (0.47) | KMT2ALMNATSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302752-A | Acetic acid derivatives and their production | ETHYL CORPORATION (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0426333-A2 | Acetic acid derivatives and their production | ETHYL CORPORATION (US) | 1991-05-08 | — | — | EP | disclosed |