Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28896831 | 0.87 | PTGS2 (0.43) | KMT2AMEN1ACHETSHRTDP1 | |
| SCHEMBL1792502 | 0.86 | ESR1 (0.53) | KMT2ASMN1; SMN2GAATSHRTDP1 | |
| SCHEMBL9232941 | 0.86 | ESR1 (0.53) | KMT2ASMN1; SMN2GAATSHRTDP1 | |
| SCHEMBL9235662 | 0.86 | ESR1 (0.53) | KMT2ASMN1; SMN2GAATSHRTDP1 | |
| SCHEMBL8429803 | 0.85 | AKR1C3 (0.46) | HTTTSHRALOX5PTGS2ALDH1A1 | |
| SCHEMBL13631372 | 0.85 | PTGS2 (0.41) | KMT2AMEN1TSHRTDP1ALOX5 | |
| SCHEMBL28435303 | 0.85 | ACHE (0.47) | KMT2AACHETSHRALOX5PTGS2 | |
| SCHEMBL7796149 | 0.85 | PSEN1 (0.50) | SMN1; SMN2GAAHTTTSHRTDP1 | |
| SCHEMBL1625348 | 0.85 | LMNA (0.55) | KMT2AMEN1SMN1; SMN2GAAHTT | |
| SCHEMBL11589410 | 0.85 | KMT2A (0.40) | KMT2AMEN1SMN1; SMN2GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111349681-A | Method for splitting 2- (4-methylphenyl) propionic acid enantiomer by using immobilized lipase to catalyze ester hydrolysis kinetics | 湖南理工学院 | 2020-06-30 | — | — | CN | claimed |
| US-12398089-B2 | Method for preparing organic carboxylic ester by using combined catalyst of aryl bidentate phosphine ligand | NANJING CHENGZHI CLEAN ENERGY CO. LTD. (CN) | 2025-08-26 | — | — | US | disclosed |
| US-20220402854-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING alpha,omega-DICARBOXYLIC ACID-TERMINATED DIALKENE ETHERS | NEUROBO PHARMACEUTICALS INC (US) | 2022-12-22 | — | — | US | disclosed |
| US-20220402854-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING alpha,omega-DICARBOXYLIC ACID-TERMINATED DIALKENE ETHERS | NEUROBO PHARMACEUTICALS INC (US) | 2022-12-22 | — | — | US | disclosed |
| US-20220298097-A1 | METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY USING COMBINED CATALYST OF ARYL BIDENTATE PHOSPHINE LIGAND | NANJING CHENGZHI CLEAN ENERGY CO. LTD. (CN) | 2022-09-22 | — | — | US | disclosed |
| CN-111057168-B | Catalyst for olefin polymerization and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-111087306-B | Method for preparing organic carboxylic ester by aryl bidentate phosphine ligand combined catalysis | 南京诚志清洁能源有限公司 | 2021-08-03 | — | — | CN | disclosed |
| WO-2021129138-A1 | METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY MEANS OF COMBINATORIAL CATALYSIS WITH ARYL BIDENTATE PHOSPHINE LIGAND | 南京诚志清洁能源有限公司 | 2021-07-01 | — | — | WO | disclosed |
| WO-2021129138-A1 | METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY MEANS OF COMBINATORIAL CATALYSIS WITH ARYL BIDENTATE PHOSPHINE LIGAND | 南京诚志清洁能源有限公司 | 2021-07-01 | — | — | WO | disclosed |
| CN-111704543-A | Process and intermediates for preparing alpha, omega-dicarboxylic acid terminated dialkyl ethers | 燿石治疗公司 | 2020-09-25 | — | — | CN | disclosed |
| US-20030078429-A1 | Process and diastereomeric salts useful for the optical resolution of racemic a-[4- (1,1-dimethylethy) phenyl) -4- (hydroxydipenylmethyl) -1-piperidinebutanol and derivative compounds | NAKAMURA MITSUO (JP) | 2003-04-24 | — | — | US | disclosed |
| WO-2002030860-A9 | KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS INC (US) | 2003-02-20 | — | — | WO | disclosed |
| WO-2002030860-A2 | KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2002-04-18 | — | — | WO | disclosed |
| EP-0759904-B1 | PROCESS AND DIASTEREOMERIC SALTS USEFUL FOR THE OPTICAL RESOLUTION OF RACEMIC 4-[4-[-4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINYL]-1-HYDROXYBUTYL]-ALPHA,ALPHA-DIMETHYLBENZENE ACETIC ACID. | MERRELL PHARMA INC (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-0711283-B1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5618811-A | Tetrahydro-1H-benzazepinones and hexahydroazepinones as selective cholecystokinin-B receptor antagonists | PFIZER INC. (US) | 1997-04-08 | — | — | US | disclosed |
| EP-0759904-A1 | PROCESS AND DIASTEREOMERIC SALTS USEFUL FOR THE OPTICAL RESOLUTION OF RACEMIC ALPHA-[4-(1,1-DIMETHYLETHYL)PHENYL]-4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINEBUTANOL AND DERIVATIVE COMPOUNDS | MERRELL PHARMACEUTICALS INC. (US) | 1997-03-05 | — | — | EP | disclosed |
| EP-0711283-A1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995031436-A1 | PROCESS AND DIASTEREOMERIC SALTS USEFUL FOR THE OPTICAL RESOLUTION OF RACEMIC α-[4-(1,1-DIMETHYLETHYL)PHENYL]-4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINEBUTANOL AND DERIVATIVE COMPOUNDS | MERRELL PHARMACEUTICALS INC. (US) | 1995-11-23 | — | — | WO | disclosed |
| WO-1995003281-A1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402854-A1 | PROCESSES AND INTERMEDIATES FOR PREPARING alpha,omega-DICARBOXYLIC ACID-TERMINATED DIALKENE ETHERS | ELOVL3, DGKI, ELOVL5 | KMT2A 3774/4885MEN1 1505/4885ACHE 2437/4885 |
| US-20030078429-A1 | Process and diastereomeric salts useful for the optical resolution of racemic a-[4- (1,1-dimethylethy) phenyl) -4- (hydroxydipenylmethyl) -1-piperidinebutanol and derivative compounds | ARRB1, HTR4, HCAR1 | KMT2A 3327/4885MEN1 2363/4885ACHE 2384/4885 |
| US-20220298097-A1 | METHOD FOR PREPARING ORGANIC CARBOXYLIC ESTER BY USING COMBINED CATALYST OF ARYL BIDENTATE PHOSPHINE LIGAND | POF1B, ADH1C, OSBP | KMT2A 3132/4885MEN1 3768/4885ACHE 2444/4885 |
| US-12398089-B2 | Method for preparing organic carboxylic ester by using combined catalyst of aryl bidentate phosphine ligand | POF1B, ADH1C, OSBP | KMT2A 3132/4885MEN1 3768/4885ACHE 2444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.