Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
| ▸ | TTPA | P49638 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656054 | 0.90 | PSEN1 (0.35) | PSEN1MEN1KMT2APDE4APDE3A | |
| SCHEMBL9313665 | 0.87 | PSEN1 (0.38) | PSEN1MEN1KMT2APDE4APDE3A | |
| SCHEMBL9313801 | 0.86 | PSEN1 (0.54) | PSEN1MEN1KMT2APDE4APDE3A | |
| SCHEMBL9313669 | 0.84 | PSEN1 (0.43) | PSEN1MEN1KMT2APDE4APDE3A | |
| SCHEMBL9655989 | 0.83 | MAPT (0.47) | MEN1KMT2ACYP4F2MAPTLMNA | |
| SCHEMBL9314082 | 0.83 | MEN1 (0.42) | PSEN1MEN1KMT2APDE4APDE3A | |
| SCHEMBL9314952 | 0.83 | PSEN1 (0.38) | PSEN1MEN1KMT2APDE4APDE3A | |
| SCHEMBL9427843 | 0.80 | AKT1 (0.35) | PSEN1MEN1KMT2APDE4APDE3A | |
| SCHEMBL9076030 | 0.79 | PSEN1 (0.44) | PSEN1MEN1KMT2APDE4APDE3A | |
| SCHEMBL9251381 | 0.79 | PSEN1 (0.45) | PSEN1TTPACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | disclosed |