Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 10/20 | 0.54 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312778 | 0.91 | PSEN1 (0.51) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL9313669 | 0.91 | PSEN1 (0.43) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL9314864 | 0.86 | PSEN1 (0.37) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL9655147 | 0.86 | PSEN1 (0.49) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL9314082 | 0.86 | MEN1 (0.42) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL9313665 | 0.85 | PSEN1 (0.38) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL9655989 | 0.83 | MAPT (0.47) | MEN1KMT2AALOX5 | |
| SCHEMBL9312779 | 0.82 | PSEN1 (0.52) | PSEN1 | |
| SCHEMBL9313892 | 0.81 | PSEN1 (0.41) | PSEN1GSTO1PTPN1MEN1KMT2A | |
| SCHEMBL9255031 | 0.80 | PSEN1 (0.50) | PSEN1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | disclosed |