Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.47 |
| ▸ | TTPA | P49638 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428539 | 0.89 | USP2 (0.46) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL9314864 | 0.83 | PSEN1 (0.37) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL9314082 | 0.83 | MEN1 (0.42) | KMT2AMEN1TTPANR1I2ALOX5 | |
| SCHEMBL9313801 | 0.83 | PSEN1 (0.54) | KMT2AMEN1ALOX5 | |
| SCHEMBL9312764 | 0.83 | MAPT (0.51) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL9313665 | 0.82 | PSEN1 (0.38) | MAPTLMNAKMT2AMEN1GSTP1 | |
| SCHEMBL9655394 | 0.82 | CYP3A4 (0.44) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL9312749 | 0.81 | BCHE (0.53) | MAPTLMNAUSP2CYP2C9KMT2A | |
| SCHEMBL9313669 | 0.81 | PSEN1 (0.43) | KMT2AMEN1ALOX5 | |
| SCHEMBL9427829 | 0.77 | PTGS1 (0.56) | CYP3A4TSHRPTGS1PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | disclosed |