SCHEMBL9314915

SCHEMBL9314915

CC(C)(CC(=O)C(F)(F)F)C(=O)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.35
CES1 P23141 7/20 0.34
CES2 O00748 4/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9314862 0.79
SCHEMBL8651750 0.76 FAAH (0.38) FAAHCES1CES2MEN1CYP1A2
SCHEMBL728692 0.75 HMGCR (0.50) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL25007292 0.72 FAAH (0.42) FAAHCES1CES2MEN1CYP1A2
SCHEMBL15105881 0.70 TSHR (0.38) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL17586556 0.70 FAAH (0.41) FAAHCES1CES2MEN1CYP1A2
SCHEMBL10254512 0.69 FAAH (0.39) FAAHCES1CES2MEN1CYP1A2
SCHEMBL30703619 0.68 TSHR (0.42) MEN1KMT2AHSD17B10HMGCRCHRM1
SCHEMBL166880 0.67 TSHR (0.40) HMGCRCHRM1TBXA2RADRA1ATSHR
SCHEMBL392087 0.67 TSHR (0.40) HMGCRCHRM1TBXA2RADRA1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5276012-A Laser-assisted CVD process forming oxide superconducting films NGK SPARK PLUG CO., LTD. (JP) 1994-01-04 US disclosed
EP-0508060-A2 Method of forming oxide superconducting films and oxide superconducting members having said films NGK Spark Plug Co. Ltd. (JP) 1992-10-14 EP disclosed