SCHEMBL931516

SCHEMBL931516

CC(=O)OCc1ccc(OC(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.47
ALDH1A1 P00352 4/20 0.45
CA2 P00918 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.38
RXRA P19793 2/20 0.37
RXRB P28702 2/20 0.37
RXRG P48443 2/20 0.37
KDM4E B2RXH2 3/20 0.36
MAPK1 P28482 2/20 0.36
GAA P10253 1/20 0.36
TMEM97 Q5BJF2 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
LMNA P02545 2/20 0.36
NR1H4 Q96RI1 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MRGPRX4 Q96LA9 1/20 0.35
CFD P00746 1/20 0.35
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL932909 0.81 ALDH1A1 (0.50) CYP3A4ALDH1A1CA2KDM4EGAA
SCHEMBL20017268 0.77 KDM4E (0.40) CYP3A4ALDH1A1CA2PTGDR2KDM4E
SCHEMBL931514 0.76 ALDH1A1 (0.51) CYP3A4ALDH1A1CA2KDM4EMAPK1
SCHEMBL14274976 0.76 ALDH1A1 (0.56) CYP3A4ALDH1A1RXRARXRB
SCHEMBL8839378 0.75 RARA (0.48) ALDH1A1RXRARXRBRXRGKDM4E
SCHEMBL6481775 0.72 ALDH1A1 (0.56) CYP3A4ALDH1A1CA2KDM4EGAA
SCHEMBL17253651 0.72 CYP3A4 (0.53) CYP3A4ALDH1A1CA2KDM4EGAA
SCHEMBL13434033 0.72 CYP3A4 (0.49) CYP3A4ALDH1A1CA2MAPK1SMN1; SMN2
SCHEMBL132773 0.72 ALDH1A1 (0.78) CYP3A4ALDH1A1CA2KDM4EMAPK1
SCHEMBL2092731 0.72 ALDH1A1 (0.60) CYP3A4ALDH1A1RXRARXRBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011005735-A1 GREEN AND ATOM-ECONOMICAL PROCESSES FOR PRODUCING PHENOLIC ANTIOXIDANTS ALBEMARLE CORPORATION (US) 2011-01-13 WO disclosed