Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.59 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.59 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.59 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.59 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315226 | 1.00 | GRIN1 (0.59) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL11800955 | 0.88 | GRIN1 (0.57) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL11800959 | 0.88 | GRIN1 (0.57) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL3067635 | 0.78 | GRIN1 (0.62) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL3067630 | 0.78 | GRIN1 (0.62) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL16443508 | 0.77 | GRIN2B (0.67) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4893125 | 0.76 | MCL1 (0.46) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4893130 | 0.76 | P2RX7 (0.45) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL4893133 | 0.76 | MCL1 (0.46) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL1275831 | 0.74 | GRIN2B (1.00) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286752-A | Antiarrhythmic diarylamidines | STERLING WINTHROP INC. (US) | 1994-02-15 | — | — | US | disclosed |