Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1186351 | 0.79 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2EPHX2POLBKMT2A | |
| SCHEMBL2936661 | 0.75 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2EPHX2POLBKMT2A | |
| SCHEMBL8338109 | 0.75 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2EPHX2POLBKMT2A | |
| SCHEMBL13074346 | 0.73 | ALDH1A1 (1.00) | ALDH1A1LMNASMN1; SMN2EPHX2POLB | |
| Hydrochloric Acid SCHEMBL11110199 | 0.73 | TDP1 (0.52) | ALDH1A1LMNAEPHX2POLBKMT2A | |
| SCHEMBL2865800 | 0.73 | KMT2A (0.56) | ALDH1A1LMNASMN1; SMN2POLBKMT2A | |
| SCHEMBL8681333 | 0.72 | ALDH1A1 (0.63) | ALDH1A1LMNASMN1; SMN2EPHX2POLB | |
| SCHEMBL6802359 | 0.72 | ALDH1A1 (0.70) | ALDH1A1LMNAEPHX2KMT2ATHRB | |
| SCHEMBL5958183 | 0.72 | ALDH1A1 (0.70) | ALDH1A1LMNAEPHX2KMT2ATHRB | |
| SCHEMBL6676537 | 0.72 | KMT2A (0.71) | ALDH1A1LMNASMN1; SMN2EPHX2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286752-A | Antiarrhythmic diarylamidines | STERLING WINTHROP INC. (US) | 1994-02-15 | — | — | US | disclosed |