Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2847686 | 0.88 | TTR (0.58) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL6676537 | 0.86 | KMT2A (0.71) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL2846389 | 0.81 | KMT2A (0.54) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL27232559 | 0.78 | AR (0.55) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL2846850 | 0.76 | PTPN7 (0.58) | KMT2A | |
| SCHEMBL29828592 | 0.76 | PTPN7 (0.58) | KMT2A | |
| SCHEMBL5527206 | 0.75 | SMN1; SMN2 (0.52) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL318068 | 0.74 | ALDH1A1 (0.73) | KMT2ALMNAALDH1A1MAPTGAA | |
| SCHEMBL9315263 | 0.73 | ALDH1A1 (0.57) | KMT2ASMN1; SMN2LMNAALDH1A1POLB | |
| SCHEMBL6673419 | 0.73 | BCHE (0.61) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099316-B1 | FLAVOUR MODULATING DERIVATIVE OF A CARBOXYLIC ACID AND A PURINE, PYRIMIDINE, NUCLEOSIDE OR NUCLEOTIDE | GIVAUDAN SA (CH) | 2017-06-21 | — | — | EP | disclosed |
| US-20130028846-A1 | Flavour Modulating Derivative of a Carboxylic Acid and a Purine, Pyrimidine, Nucleoside, or Nucleotide | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2013-01-31 | — | — | US | disclosed |
| US-8293215-B2 | Flavour modulating derivative of a carboxylic acid and a purine, pyrimidine, nucleoside, or nucleotide | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2012-10-23 | — | — | US | disclosed |
| US-20100129515-A1 | FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2010-05-27 | — | — | US | disclosed |
| US-20100074850-A1 | Flavour Modulating Derivative of a Carboxylic Acid and a Purine, Pyrimidine, Nucleoside, or Nucleotide | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100074850-A1 | Flavour Modulating Derivative of a Carboxylic Acid and a Purine, Pyrimidine, Nucleoside, or Nucleotide | NUDT1, GART, UMPS | KMT2A 3853/4885SMN1; SMN2 1697/4885LMNA 4231/4885 |
| US-20130028846-A1 | Flavour Modulating Derivative of a Carboxylic Acid and a Purine, Pyrimidine, Nucleoside, or Nucleotide | NUDT1, GART, UMPS | KMT2A 3846/4885SMN1; SMN2 1741/4885LMNA 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.