SCHEMBL8759752

SCHEMBL8759752

C=Cc1ccc(COCCC[Si](OC)(OC)OC)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 2/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
TRPA1 O75762 1/20 0.32
PPARG P37231 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
TP53 P04637 2/20 0.31
CYP3A4 P08684 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
ALOX12 P18054 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12036684 0.91 ALDH1A1 (0.35) TDP1L3MBTL1ALDH1A1CHRNB2CHRNB4
SCHEMBL8759059 0.87 TDP1 (0.35) TDP1L3MBTL1ALDH1A1CHRNB2CHRNB4
SCHEMBL9314689 0.87 TDP1 (0.35) TDP1L3MBTL1ALDH1A1CHRNB2CHRNB4
SCHEMBL9315283 0.85 CHRNB2 (0.33) TDP1L3MBTL1ALDH1A1CHRNB2CHRNB4
SCHEMBL9315480 0.83 TDP1 (0.36) TDP1L3MBTL1TRPA1MEN1KMT2A
SCHEMBL9315362 0.82 CHRNB2 (0.35) TDP1L3MBTL1ALDH1A1CHRNB2CHRNB4
SCHEMBL9315259 0.82 ALDH1A1 (0.33) TDP1L3MBTL1ALDH1A1CHRNB2CHRNB4
SCHEMBL316695 0.82 ALDH1A1 (0.46) TDP1L3MBTL1ALDH1A1CHRNB2CHRNB4
SCHEMBL316600 0.82 ALDH1A1 (0.46) TDP1L3MBTL1ALDH1A1CHRNB2CHRNB4
SCHEMBL9316449 0.81 ALDH1A1 (0.35) TDP1L3MBTL1ALDH1A1CHRNB2CHRNB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5326895-A 3-(vinylbenzyloxy)propylsilane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-07-05 US claimed
JP-5032679-A None JP disclosed
US-8063162-B2 Polymer for an ink receiving layer of an inkjet recording element HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2011-11-22 US disclosed
US-20110160416-A1 POLYMER FOR AN INK RECEIVING LAYER OF AN INKJET RECORDING ELEMENT CHEN TIENTEH 2011-06-30 US disclosed
US-7923117-B2 first monomer of the polymer includes at least one amine functional group; aminoethylmethacrylate; aminoethylacrylate; second monomer includes a carbon backbone having at least one silane functional group pendant; prevent dye from migrating HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2011-04-12 US disclosed
US-20080182936-A1 POLYMER FOR AN INK RECEIVING LAYER OF AN INKJET RECORDING ELEMENT HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2008-07-31 US disclosed
EP-0494549-B1 3-(Vinylbenzyloxy)propylsilane compounds and their preparation SHINETSU CHEMICAL CO (JP) 1997-05-28 EP disclosed
US-5342983-A Polymer reforming agents SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-08-30 US disclosed
US-5326895-A 3-(vinylbenzyloxy)propylsilane compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-07-05 US disclosed
JP-H0532679-A 3-(VINYLBENZYLOXY)PROPYLSILANE COMPOUND SHIN ETSU CHEM CO LTD 1993-02-09 JP disclosed
EP-0494549-A1 3-(Vinylbenzyloxy)propylsilane compounds, their preparation and polymers thereof Shin-Etsu Chemical Co., Ltd. (JP) 1992-07-15 EP disclosed