Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315909 | 0.82 | CHRNB2 (0.49) | PPARASMN1; SMN2ALDH1A1CHRNA7HPGD | |
| SCHEMBL6280406 | 0.81 | TDP1 (0.42) | TLR4TLR2FURINTDP1TP53 | |
| SCHEMBL9315822 | 0.80 | TP53 (0.34) | TDP1TP53 | |
| SCHEMBL25515931 | 0.78 | TLR4 (0.40) | TLR4TLR2FURINTDP1TP53 | |
| SCHEMBL8361886 | 0.78 | TSHR (0.56) | TP53ALDH1A1GGPS1 | |
| SCHEMBL412094 | 0.77 | TLR4 (0.60) | TLR4TLR2FURINTDP1TP53 | |
| SCHEMBL30988603 | 0.77 | TDP1 (0.41) | TLR4TLR2FURINTDP1TP53 | |
| SCHEMBL2623207 | 0.76 | TSHR (0.57) | TLR4TLR2KMT2AGGPS1 | |
| SCHEMBL10071523 | 0.76 | FURIN (0.50) | TLR4TLR2FURINTDP1TP53 | |
| SCHEMBL10071513 | 0.76 | MAPK1 (0.49) | TLR4TLR2FURINTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342983-A | Polymer reforming agents | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-08-30 | — | — | US | disclosed |