SCHEMBL9315822

SCHEMBL9315822

C=Cc1cccc(COCCCC(C)(C)O[SiH3])c1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NAAA Q02083 1/20 0.32
HMGCR P04035 1/20 0.31
TEAD3 Q99594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9314684 0.84 ALDH1A1 (0.31) TDP1
SCHEMBL9315495 0.80 TLR4 (0.39) TP53TDP1
SCHEMBL7871006 0.79 TDP1 (0.41) TP53TDP1NAAATEAD3
SCHEMBL10071517 0.78 PLA2G4B (0.40) TP53TDP1NAAA
SCHEMBL10071521 0.78 TDP1 (0.40) TP53TDP1NAAATEAD3
SCHEMBL10071516 0.78 TDP1 (0.40) TP53TDP1NAAATEAD3
SCHEMBL10071528 0.77 TDP1 (0.40) TP53TDP1NAAATEAD3
SCHEMBL14732698 0.77 TDP1 (0.39) TP53TDP1NAAA
SCHEMBL10071515 0.77 PLA2G4B (0.42) TP53TDP1
SCHEMBL10071510 0.77 PLA2G4B (0.42) TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5342983-A Polymer reforming agents SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-08-30 US disclosed