⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4643088 | 1.00 | TSHR (0.33) | — | |
| SCHEMBL2281821 | 1.00 | TSHR (0.33) | — | |
| SCHEMBL4641274 | 1.00 | TSHR (0.33) | — | |
| SCHEMBL4643637 | 1.00 | TSHR (0.33) | — | |
| SCHEMBL4641353 | 1.00 | TSHR (0.33) | — | |
| SCHEMBL1481861 | 1.00 | TSHR (0.33) | — | |
| SCHEMBL4641445 | 1.00 | TSHR (0.33) | — | |
| SCHEMBL93131 | 1.00 | TSHR (0.33) | — | |
| SCHEMBL2277028 | 1.00 | TSHR (0.33) | — | |
| SCHEMBL4646590 | 1.00 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 352 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023297-A | SUBSTITUTED HYDANTOIN AND THIOHYDANTOIN DERIVATIVES AS ANDROGEN RECEPTOR ANTAGONISTS | 詹森药业有限公司 | 2019-07-16 | — | — | CN | claimed |
| CN-106459067-A | Imidazo[1,2-A]pyrazin-1yl-benzamide compounds for treating spinal muscular atrophy | 豪夫迈·罗氏有限公司 | 2017-02-22 | — | — | CN | claimed |
| JP-2011503331-A | — | — | 2011-01-27 | — | — | JP | claimed |
| US-20030195311-A1 | Multi-component liquid azo-peroxide initiator mixture and method for using same | CROMPTON CORPORATION | 2003-10-16 | — | — | US | claimed |
| EP-0847383-A1 | MULTI-COMPONENT LIQUID AZODINITRILE MIXTURES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-17 | — | — | EP | claimed |
| US-5760192-A | FREE RADICAL, POLYMERIZATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-02 | — | — | US | claimed |
| WO-1997008137-A1 | MULTI-COMPONENT LIQUID AZODINITRILE MIXTURES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-03-06 | — | — | WO | claimed |
| EP-0623116-A1 | AMINO ACID DERIVATIVES AS PAF-RECEPTOR ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-11-09 | — | — | EP | claimed |
| EP-0558094-A1 | Pyridine compounds for treating amnesia | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1993-09-01 | — | — | EP | claimed |
| WO-1993014072-A1 | AMINO ACID DERIVATIVES AS PAF-RECEPTOR ANTAGONISTS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-07-22 | — | — | WO | claimed |
| US-5084214-A | Compounds for the treatment of artheriosclerosis | SHIONOGI & CO., LTD. (JP) | 1992-01-28 | — | — | US | claimed |
| US-20240226132-A1 | RNA COMPOSITIONS COMPRISING A BUFFER SUBSTANCE AND METHODS FOR PREPARING, STORING AND USING THE SAME | BIONTECH DELIVERY TECHNOLOGIES GMBH (DE) | 2024-07-11 | — | — | US | disclosed |
| WO-2024133635-A1 | COMPOSITION | BIONTECH DELIVERY TECHNOLOGIES GMBH (DE) | 2024-06-27 | — | — | WO | disclosed |
| US-20240191009-A1 | POLYFUNCTIONALIZED HIGH-CIS 1,4-POLYBUTADIENE AND METHOD FOR MANUFACTURING THE SAME | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2024-06-13 | — | — | US | disclosed |
| US-20240191030-A1 | RESIN COMPOSITION, CURED OBJECT, RESIN SHEET, PREPREG, METAL-CLAD LAMINATE, MULTILAYERED PRINTED WIRING BOARD, SEALING MATERIAL, FIBER-REINFORCED COMPOSITE MATERIAL, ADHESIVE, AND SEMICONDUCTOR DEVICE | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2024-06-13 | — | — | US | disclosed |
| US-4206215-A | Antimicrobial bis-[4-(substituted-amino)-1-pyridinium]alkanes | STERLING DRUG INC. (US) | 1980-06-03 | — | — | US | disclosed |
| US-4152518-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1979-05-01 | — | — | US | disclosed |
| US-4112105-A | Anti-inflammatory 3-(substituted-amino)-2,1-benzisothiazoles | STERLING DRUG INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-3996263-A | ANTIULCER | SANKYO COMPANY LIMITED (JA) | 1976-12-07 | — | — | US | disclosed |
| US-3983152-A | OXYTOCICS | SANKYO COMPANY LIMITED (JA) | 1976-09-28 | — | — | US | disclosed |