Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA7 | P43166 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9221432 | 0.83 | CA12 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9046702 | 0.82 | CA12 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8564502 | 0.80 | CA12 (0.77) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9317239 | 0.79 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9567431 | 0.77 | CA12 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8959278 | 0.76 | SLC6A3 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2339088 | 0.76 | CA12 (0.79) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28263768 | 0.76 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29593170 | 0.74 | THRB (0.71) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1237641 | 0.74 | THRB (0.71) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426476-B1 | Pyrimidine derivatives, their production and use | SUMITOMO CHEMICAL CO (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5300640-A | Herbicide intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-04-05 | — | — | US | disclosed |
| EP-0549344-A1 | Triazine derivatives as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-5125957-A | Pre- and postemergence herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-30 | — | — | US | disclosed |
| EP-0426476-A1 | Pyrimidine derivatives, their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-08 | — | — | EP | disclosed |