SCHEMBL9315899

SCHEMBL9315899

CC(CCC(=O)O)SSC(C)CCC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.54
GABRD O14764 2/20 0.54
GABRA1 P14867 2/20 0.54
GABRB1 P18505 2/20 0.54
GABRG2 P18507 2/20 0.54
GABRB3 P28472 2/20 0.54
GABRA5 P31644 2/20 0.54
GABRA3 P34903 2/20 0.54
GABRA2 P47869 2/20 0.54
GABRB2 P47870 2/20 0.54
GABRA4 P48169 2/20 0.54
GABRE P78334 2/20 0.54
GABRA6 Q16445 2/20 0.54
GABRG1 Q8N1C3 2/20 0.54
GABRG3 Q99928 2/20 0.54
GABRQ Q9UN88 2/20 0.54
CYP1A2 P05177 2/20 0.54
TET2 Q6N021 3/20 0.44
KDM4A O75164 2/20 0.44
KDM4C Q9H3R0 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1751466 0.88 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL1752703 0.88 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL1752252 0.88 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29282935 0.87 GABRP (0.43) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL11559068 0.85 TSHR (0.46) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL18087340 0.84 GABRP (0.45) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL29282934 0.83 FOLH1 (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL10961589 0.82
SCHEMBL27820216 0.81 TSHR (0.42) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL6695222 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063413-A Cabazitaxel triglyceride prodrug, and preparation method and application thereof 沈阳药科大学 2024-05-24 CN claimed
US-5342724-A Preparing polyester from diol and diacid wherein one of the monomers has disulfuide linkage, reacting polyester with unsaturated monomer to create addition polymer blocks linked by sulfide group from dislufide linkage EASTMAN KODAK COMPANY (US) 1994-08-30 US claimed
WO-2024179213-A1 CHOPPED FIBER COMPOSITE MATERIAL AND PREPARATION METHOD THEREFOR, AND TELEVISION REAR SHELL AND PREPARATION METHOD THEREFOR 惠州视维新技术有限公司 2024-09-06 WO disclosed
CN-118063413-A Cabazitaxel triglyceride prodrug, and preparation method and application thereof 沈阳药科大学 2024-05-24 CN disclosed
CN-114891320-B Epoxy resin/chopped glass fiber composite material and preparation method thereof 重庆国际复合材料股份有限公司 2023-09-19 CN disclosed
CN-114891320-A Epoxy resin/chopped glass fiber composite material and preparation method thereof 重庆国际复合材料股份有限公司 2022-08-12 CN disclosed
US-9518017-B2 Purification of intermediates used in the preparation of heterobifunctional linkers IMMUNOGEN, INC. (US) 2016-12-13 US disclosed
US-9518017-B2 Purification of intermediates used in the preparation of heterobifunctional linkers IMMUNOGEN, INC. (US) 2016-12-13 US disclosed
US-20160137604-A1 PURIFICATION OF INTERMEDIATES USED IN THE PREPARATION OF HETEROBIFUNCTIONAL LINKERS IMMUNOGEN, INC. 2016-05-19 US disclosed
US-20160137604-A1 PURIFICATION OF INTERMEDIATES USED IN THE PREPARATION OF HETEROBIFUNCTIONAL LINKERS IMMUNOGEN, INC. 2016-05-19 US disclosed
US-5342724-A Preparing polyester from diol and diacid wherein one of the monomers has disulfuide linkage, reacting polyester with unsaturated monomer to create addition polymer blocks linked by sulfide group from dislufide linkage EASTMAN KODAK COMPANY (US) 1994-08-30 US disclosed
US-4141734-A SUBSTITUTED ORGANIC DI- OR TRISULFIDE ANTIDEPOSIT AGENTS CIBA-GEIBY AG (CH) 1979-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160137604-A1 PURIFICATION OF INTERMEDIATES USED IN THE PREPARATION OF HETEROBIFUNCTIONAL LINKERS MCM5, SMCHD1, BMP2 GABRP 2261/4885GABRD 1812/4885GABRA1 2427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.