Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31538763 | 1.00 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL18241564 | 0.85 | ALDH1A1 (0.45) | MEN1KMT2AGAASMN1; SMN2MAPT | |
| SCHEMBL9314623 | 0.77 | ALDH1A1 (0.45) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL28609695 | 0.76 | ALDH1A1 (0.64) | NPC1RAB9AMAPTLMNATRPA1 | |
| SCHEMBL9633590 | 0.76 | ALDH1A1 (0.64) | NPC1RAB9AMAPTLMNATRPA1 | |
| SCHEMBL9315944 | 0.75 | TSHR (0.54) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL31538759 | 0.75 | TSHR (0.54) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL9314769 | 0.75 | TSHR (0.50) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL31538754 | 0.75 | TSHR (0.50) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL9316413 | 0.74 | CA1 (0.59) | NPC1RAB9ASMN1; SMN2MAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310620-A | Alkali-soluble nitrone compounds and contrast enhanced material comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |