Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31538754 | 1.00 | TSHR (0.50) | TSHRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9315446 | 0.76 | NFE2L2 (0.50) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL31538748 | 0.76 | NFE2L2 (0.50) | NPC1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL9321637 | 0.75 | XDH (0.57) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL9315902 | 0.75 | NPC1 (0.49) | TSHRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL31538763 | 0.75 | NPC1 (0.49) | TSHRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5332767 | 0.70 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL33663 | 0.68 | TSHR (1.00) | TSHRSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL5335033 | 0.68 | TRPA1 (0.61) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL5335032 | 0.68 | TRPA1 (0.61) | NPC1RAB9ASMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310620-A | Alkali-soluble nitrone compounds and contrast enhanced material comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |