Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | LAP3 | P28838 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21247440 | 1.00 | EPHX1 (0.55) | EPHX1SLC1A3SLC1A2SLC1A1ALPI | |
| SCHEMBL157788 | 0.84 | CYP1A2 (0.57) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL157789 | 0.84 | CYP1A2 (0.57) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL2466759 | 0.84 | CYP1A2 (0.57) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL3901603 | 0.83 | ALDH1A1 (0.58) | EPHX1SLC1A3SLC1A2SLC1A1ALPI | |
| SCHEMBL1432589 | 0.83 | ALDH1A1 (0.58) | EPHX1SLC1A3SLC1A2SLC1A1ALPI | |
| SCHEMBL20791653 | 0.83 | ALDH1A1 (0.58) | EPHX1SLC1A3SLC1A2SLC1A1ALPI | |
| Ammonia Solution, Strong SCHEMBL8346946 | 0.82 | CYP1A2 (0.55) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL27996592 | 0.82 | CYP1A2 (0.55) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| Water SCHEMBL28204086 | 0.82 | CYP1A2 (0.55) | SLC1A3SLC1A2SLC1A1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192764-A1 | NOVEL DOPAMINE PRECURSORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2023-06-22 | — | — | US | disclosed |
| US-20210363181-A1 | DOPAMINE PRECURSORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2021-11-25 | — | — | US | disclosed |
| EP-3749677-A1 | DOPAMINE PRECURSORS | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd (IL) | 2020-12-16 | — | — | EP | disclosed |
| WO-2019155464-A1 | DOPAMINE PRECURSORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) | 2019-08-15 | — | — | WO | disclosed |
| CN-108495617-A | Including the pharmaceutical composition of levodopa amide and its purposes | 纽罗德姆有限公司 | 2018-09-04 | — | — | CN | disclosed |
| US-5298144-A | Chemically wired fructose dehydrogenase electrodes | THE YELLOW SPRINGS INSTRUMENT COMPANY, INC. (US) | 1994-03-29 | — | — | US | disclosed |
| EP-0278647-A3 | ELECTRONCHEMICAL PROCESSES INVOLVING ENZYMES | AT&T Corp. (US) | 1989-09-20 | — | — | EP | disclosed |
| EP-0278647-A2 | Electronchemical processes involving enzymes | AT&T Corp. (US) | 1988-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192764-A1 | NOVEL DOPAMINE PRECURSORS | SNCA, DBH, PARK7 | EPHX1 2045/4885SLC1A3 203/4885SLC1A2 75/4885 |
| US-20210363181-A1 | DOPAMINE PRECURSORS | SNCA, DBH, PARK7 | EPHX1 2046/4885SLC1A3 170/4885SLC1A2 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.