SCHEMBL9316145

SCHEMBL9316145

Oc1cc2cc[nH]c2c(O)c1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.39
ALOX15 P16050 2/20 0.39
TYR P14679 1/20 0.39
USP2 O75604 1/20 0.39
RAD51 Q06609 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
GUSB P08236 5/20 0.37
TNF P01375 1/20 0.36
RIPK1 Q13546 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
DAO P14920 1/20 0.35
DDO Q99489 1/20 0.35
IKBKB O14920 4/20 0.35
CHUK O15111 4/20 0.35
AHR P35869 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
INPPL1 O15357 1/20 0.34
NSD2 O96028 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24625869 0.81 DAO (0.36) GAAALOX15TYRUSP2RAD51
SCHEMBL4424880 0.76 TYR (0.38) GAAALOX15TYRUSP2RAD51
SCHEMBL1875458 0.74 TNF (0.42) GAAALOX15TYRUSP2RAD51
SCHEMBL1741436 0.74 TNF (0.38) GAAALOX15TYRUSP2RAD51
SCHEMBL8649018 0.74 DAO (0.37) GAAALOX15TYRUSP2RAD51
SCHEMBL8620419 0.73 USP2 (0.48) GAAALOX15TYRUSP2RAD51
SCHEMBL4419394 0.72 TYR (0.48) GAAALOX15TYRUSP2RAD51
SCHEMBL28621811 0.72 TRPM4 (0.52) GAATYRIKBKBCHUKAHR
SCHEMBL4421162 0.71 CSNK2A1 (0.34) GAAALOX15TYRUSP2RAD51
SCHEMBL17064178 0.70 TNF (0.35) GAAALOX15TYRUSP2RAD51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5354870-A Hair dyes L'OREAL (FR) 1994-10-11 US disclosed
US-5131911-A Hair dyes L'OREAL (FR) 1992-07-21 US disclosed