Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 4/20 | 0.35 |
| ▸ | CHUK | O15111 | 4/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1997793 | 0.78 | ALOX15 (0.45) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL1960195 | 0.78 | USP2 (0.45) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL22253018 | 0.78 | SELL (0.41) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL17064186 | 0.78 | AHR (0.50) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL5372066 | 0.78 | ALOX15 (0.45) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL23847838 | 0.75 | MCL1 (0.38) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL20314900 | 0.74 | USP2 (0.41) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL23735763 | 0.74 | USP2 (0.41) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL22241996 | 0.74 | TRPA1 (0.44) | USP2GAAALOX15RAD51NPSR1 | |
| SCHEMBL20667383 | 0.74 | GABRA1 (0.41) | USP2GAAALOX15RAD51NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776977-B1 | Process for the preparation of indol compounds | OREAL (FR) | 1998-05-27 | — | — | EP | claimed |
| US-5717108-A | MODIFIED WITH ONE OR TWO HYDROXY GROUP(S); ONE STEP USING AN HYDROLASE | L'OREAL (FR) | 1998-02-10 | — | — | US | claimed |
| EP-0776977-A1 | Process for the preparation of indol compounds | L'OREAL (FR) | 1997-06-04 | — | — | EP | claimed |
| EP-0776977-B1 | Process for the preparation of indol compounds | OREAL (FR) | 1998-05-27 | — | — | EP | disclosed |
| US-5717108-A | MODIFIED WITH ONE OR TWO HYDROXY GROUP(S); ONE STEP USING AN HYDROLASE | L'OREAL (FR) | 1998-02-10 | — | — | US | disclosed |
| EP-0776977-A1 | Process for the preparation of indol compounds | L'OREAL (FR) | 1997-06-04 | — | — | EP | disclosed |