Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8994492 | 0.69 | MAPK14 (0.46) | AHRMAPK14CYP1B1KMOLMNA | |
| SCHEMBL8994490 | 0.68 | MAPK14 (0.42) | AHRMAPK14CYP1B1KMOLMNA | |
| SCHEMBL9019133 | 0.67 | MAPK14 (0.41) | AHRMAPK14CYP1B1KMOLMNA | |
| SCHEMBL9019127 | 0.66 | MAOB (0.43) | AHRMAPK14CYP1B1KMOLMNA | |
| SCHEMBL9316754 | 0.65 | AHR (0.38) | AHRMAPK14CYP1B1KMOLMNA | |
| SCHEMBL9019071 | 0.64 | MAOB (0.39) | AHRMAPK14CYP1B1KMOLMNA | |
| SCHEMBL27260508 | 0.64 | AHR (0.41) | AHRMAPK14CYP1B1KMOALDH1A1 | |
| SCHEMBL9019167 | 0.62 | MAPK14 (0.40) | AHRMAPK14CYP1B1KMOLMNA | |
| SCHEMBL9222935 | 0.62 | AHR (0.39) | AHRMAPK14CYP1B1KMOLMNA | |
| SCHEMBL9316592 | 0.62 | PTGS1 (0.37) | AHRMAPK14CYP1B1KMOMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310938-A | Miticides, insecticides, parasiticides, and anthelmintics | AMERICAN CYANAMID COMPANY (US) | 1994-05-10 | — | — | US | claimed |