Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ARF6 | P62330 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 4/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.31 |
| ▸ | KIF20B | Q96Q89 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316723 | 0.86 | PTGS1 (0.38) | PTGS1PTGS2ARF6NOTUMKMT2A | |
| SCHEMBL9316754 | 0.78 | AHR (0.38) | AHRNOTUMKMT2AMEN1MAPK14 | |
| SCHEMBL8799224 | 0.76 | AHR (0.33) | AHRNOTUMKMT2AMEN1CRHBP | |
| SCHEMBL9316607 | 0.76 | AHR (0.45) | AHRNOTUMKMT2AMEN1MAPK14 | |
| SCHEMBL9316608 | 0.68 | KIF11 (0.42) | NOTUMKMT2ARAD51 | |
| SCHEMBL9056721 | 0.64 | ARF6 (0.35) | ARF6AHRNOTUMKMT2AMEN1 | |
| SCHEMBL9054925 | 0.64 | MAPK14 (0.33) | ARF6AHRNOTUMKMT2AMEN1 | |
| SCHEMBL8799050 | 0.62 | KDM4E (0.32) | KMT2AMEN1CRHBPCRHR2 | |
| SCHEMBL8799397 | 0.62 | AHR (0.36) | PTGS1PTGS2AHRKMT2AMEN1 | |
| SCHEMBL27259909 | 0.62 | AR (0.51) | AHRMAPK14KMOCYP1B1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310938-A | Miticides, insecticides, parasiticides, and anthelmintics | AMERICAN CYANAMID COMPANY (US) | 1994-05-10 | — | — | US | claimed |