Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 4/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019044 | 0.83 | MAOA (0.38) | MAOAMAOBPOLBHTTALOX15 | |
| SCHEMBL9019167 | 0.82 | MAPK14 (0.40) | MAPK14AHRKMOIDO1POLB | |
| SCHEMBL9019071 | 0.79 | MAOB (0.39) | MAPK14AHRKMOMAOAMAOB | |
| SCHEMBL8994492 | 0.76 | MAPK14 (0.46) | MAPK14AHRKMOMAOAIDO1 | |
| SCHEMBL8994490 | 0.75 | MAPK14 (0.42) | MAPK14AHRKMOIDO1ADORA2A | |
| SCHEMBL9023409 | 0.74 | CCR2 (0.46) | MAPK14AHRKMOMAOAMAOB | |
| SCHEMBL27260508 | 0.68 | AHR (0.41) | MAPK14AHRKMOIDO1AR | |
| SCHEMBL10591229 | 0.67 | MAPK14 (0.43) | MAPK14AHRKMOIDO1ADORA2A | |
| SCHEMBL9224323 | 0.67 | MAPK14 (0.40) | MAPK14AHRKMOMAOAIDO1 | |
| SCHEMBL9316192 | 0.67 | AHR (0.39) | MAPK14AHRKMOMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434940-B1 | N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID CO (US) | 1996-05-29 | — | — | EP | claimed |
| US-5102904-A | N-OXYGENATED ARYLPYRROLE INSECTICIDAL, ACARICIDAL AND NEMATICIDAL AGENTS AND USE THEREAS | AMERICAN CYANAMID COMPANY (US) | 1992-04-07 | — | — | US | claimed |
| EP-0434940-A2 | N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1991-07-03 | — | — | EP | claimed |