Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316132 | 1.00 | NLRP3 (0.50) | NLRP3NFKB1NFKB2RELALMNA | |
| SCHEMBL8682007 | 0.81 | NLRP3 (0.45) | NLRP3NFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL8682000 | 0.81 | NLRP3 (0.45) | NLRP3NFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL11950435 | 0.71 | — | — | |
| SCHEMBL420322 | 0.71 | LMNA (0.53) | NLRP3LMNAALDH1A1POLB | |
| SCHEMBL8335902 | 0.71 | LMNA (0.53) | NLRP3LMNAALDH1A1POLB | |
| SCHEMBL10549315 | 0.70 | NLRP3 (0.43) | NLRP3LMNAALDH1A1POLB | |
| SCHEMBL5878605 | 0.68 | CYP1A2 (0.45) | NFKB1NFKB2RELALMNAALDH1A1 | |
| SCHEMBL8683550 | 0.68 | — | — | |
| SCHEMBL8683554 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374766-A | Esterification of the cooresponding alcohol with an anhydride in presence of lipase | NITTO DENKO CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |