Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7178642 | 0.86 | ALDH1A1 (0.55) | ALDH1A1TSHRMMP8LMNAPOLB | |
| SCHEMBL9091746 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TSHRMMP8POLBMAPT | |
| SCHEMBL8999335 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRMMP8LMNAPOLB | |
| SCHEMBL10908314 | 0.80 | HPGD (0.56) | ALDH1A1MMP8LMNAPOLBMAPT | |
| SCHEMBL28514782 | 0.80 | NPSR1 (0.54) | ALDH1A1TSHRMMP8LMNAPOLB | |
| SCHEMBL10582684 | 0.79 | LMNA (0.54) | ALDH1A1LMNAPOLBMAPTHPGD | |
| SCHEMBL13715562 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TSHRMMP8LMNAPOLB | |
| SCHEMBL6341119 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TSHRMMP8LMNAPOLB | |
| SCHEMBL435220 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TSHRMMP8LMNAPOLB | |
| SCHEMBL13715452 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TSHRMMP8LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278326-A | Aromatic | WARNER-LAMBERT COMPANY (US) | 1994-01-11 | — | — | US | disclosed |
| US-4042596-A | 2-Alkyl-5-phenethyl-4-oxazolecarboxylic acids and derivatives | SANDOZ, INC. (US) | 1977-08-16 | — | — | US | disclosed |
| US-3994915-A | Preparation of substituted oxazoles | SANDOZ, INC. (US) | 1976-11-30 | — | — | US | disclosed |