Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316885 | 0.88 | KDM4E (0.49) | KDM4EHPGD | |
| SCHEMBL9317355 | 0.86 | PPARG (0.49) | KDM4EHPGD | |
| SCHEMBL9316768 | 0.81 | HPGD (0.48) | MAPTKDM4ETP53POLBHPGD | |
| SCHEMBL9316762 | 0.81 | HPGD (0.48) | MAPTKDM4ETP53POLBHPGD | |
| SCHEMBL6157782 | 0.78 | FFAR1 (0.65) | MAPTKDM4ETP53 | |
| SCHEMBL4746469 | 0.76 | PPARG (0.73) | — | |
| SCHEMBL5795341 | 0.75 | KDM4E (0.54) | KDM4EHPGD | |
| SCHEMBL6970285 | 0.75 | PPARG (0.65) | — | |
| SCHEMBL7737825 | 0.74 | SMO (0.51) | KDM4EPOLBHPGD | |
| SCHEMBL12468962 | 0.74 | MAPT (0.69) | MAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330998-A | Anticholesterol agents | PFIZER INC. (US) | 1994-07-19 | — | — | US | disclosed |