Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.49 |
| ▸ | PPARA | Q07869 | 15/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316885 | 0.93 | KDM4E (0.49) | PPARGPPARAPPARDKDM4EHRH3 | |
| SCHEMBL9316495 | 0.86 | MAPT (0.53) | KDM4EHPGD | |
| SCHEMBL6970285 | 0.83 | PPARG (0.65) | PPARGPPARAPPARD | |
| SCHEMBL9316442 | 0.82 | PIM1 (0.44) | PPARGPPARAPPARDHRH3HPGD | |
| SCHEMBL9316443 | 0.82 | PIM1 (0.44) | PPARGPPARAPPARDHRH3HPGD | |
| SCHEMBL4746469 | 0.79 | PPARG (0.73) | PPARGPPARAPPARD | |
| SCHEMBL9316718 | 0.77 | HRH3 (0.50) | PPARGPPARAPPARDKDM4EHRH3 | |
| SCHEMBL5795341 | 0.76 | KDM4E (0.54) | PPARGPPARAPPARDKDM4EHRH3 | |
| SCHEMBL9316520 | 0.75 | PIM1 (0.45) | PPARGPPARAKDM4EHRH3HPGD | |
| SCHEMBL9370030 | 0.75 | PIM1 (0.45) | PPARGPPARAKDM4EHRH3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330998-A | Anticholesterol agents | PFIZER INC. (US) | 1994-07-19 | — | — | US | disclosed |
| WO-1989008652-A1 | THIAZOLIDINEDIONE DERIVATIVES AS HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1989-09-21 | — | — | WO | disclosed |