Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316754 | 0.76 | AHR (0.38) | AHRCYP1B1KMONPC1RAB9A | |
| SCHEMBL9316592 | 0.76 | PTGS1 (0.37) | AHRCYP1B1KMOMEN1KMT2A | |
| SCHEMBL9518713 | 0.72 | AHR (0.50) | AHRCYP1B1KMONPC1RAB9A | |
| SCHEMBL9222935 | 0.70 | AHR (0.39) | AHRCYP1B1KMOKDM4EALDH1A1 | |
| SCHEMBL9519411 | 0.68 | AHR (0.45) | AHRCYP1B1NPC1RAB9AKDM4E | |
| SCHEMBL9472032 | 0.68 | — | — | |
| SCHEMBL27259909 | 0.67 | AR (0.51) | AHRCYP1B1KMOALOX15LMNA | |
| SCHEMBL137915 | 0.66 | AHR (1.00) | AHRCYP1B1KMONPC1RAB9A | |
| SCHEMBL29769221 | 0.66 | AHR (1.00) | AHRCYP1B1KMONPC1RAB9A | |
| SCHEMBL27259911 | 0.66 | AHR (0.42) | AHRCYP1B1KMONPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347488-B1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID CO (US) | 1994-06-01 | — | — | EP | claimed |
| US-5310938-A | Miticides, insecticides, parasiticides, and anthelmintics | AMERICAN CYANAMID COMPANY (US) | 1994-05-10 | — | — | US | claimed |