Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9315820 | 0.85 | MEN1 (0.58) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL9316074 | 0.85 | KDM4E (0.45) | MEN1KMT2AMAPTMCL1GSK3B | |
| SCHEMBL9316614 | 0.81 | MEN1 (0.51) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL9314846 | 0.77 | BAZ2B (0.46) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL9314877 | 0.76 | KMT2A (0.46) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL9315615 | 0.75 | PTGDR2 (0.48) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL9316061 | 0.75 | BAZ2B (0.45) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL9315614 | 0.75 | PTGDR2 (0.48) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL9315583 | 0.75 | MAPT (0.48) | MEN1KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL9314841 | 0.74 | BAZ2B (0.45) | MEN1KMT2AMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5281608-A | Antiinflammatory agents and interleukin II antagonist | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-01-25 | — | — | US | disclosed |